This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Topic Collections  • Genetics, Other  • Alert me on articles by topic

Tracy Hampton, PhD

JAMA. 2005;294:783-784.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

San Francisco—Nuclear cloning holds great promise for curing or alleviating a number of diseases and conditions. Apart from various ethical considerations, the technique has a number of technical hurdles to clear before it has a chance of making its way into the clinic.

Nuclear cloning (also called nuclear transfer) involves replacing the DNA of a donated egg with the DNA from a patient’s cell and coaxing the egg to divide and produce embryonic stem cells. These are then manipulated and introduced back into the patient. Although a group of researchers in South Korea recently succeeded in using patient DNA in nuclear cloning to derive 11 new human embryonic stem cell lines (Hwang et al. Science. 2005;308:1777-1783), many efforts remain unsuccessful, and scientists are keen to find strategies for making nuclear cloning more efficient.

Researchers are continually trying to improve therapeutic nuclear cloning techniques, which involve . . . [Full Text of this Article]

CLUES WITHIN CELLS