 |
|
Thrombosis After Implantation of Drug-Eluting Stents—Reply
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
In Reply: Dr Marret and colleagues raise questions about the reasons for premature antiplatelet therapy discontinuation and the timing between interruption and the acute coronary event. Regarding the former, in 17 patients who prematurely discontinued the dual-antiplatelet therapy, the reasons were surgery in 7 (41%), intolerance or bleeding in 6 (35%), and poor adherence in 4 (24%). Stent thrombosis occurred in 5 of the 17 patients (29%) who discontinued therapy: due to surgery in 2, due to intolerance or bleeding in 2, and due to poor adherence in 1. In 4 patients, both aspirin and clopidogrel were discontinued; in 1 patient only clopidogrel was discontinued. Patients experienced an acute thrombotic event ranging from 1 to 30 days after antiplatelet therapy discontinuation.
In our study cohort, 2 additional patients who discontinued dual-antiplatelet therapy after the assigned time experienced late stent thrombosis. This observation raises concern regarding the adequacy of the current . . . [Full Text of this Article]
Ioannis Iakovou, MD;
Antonio Colombo, MD
info@emocolumbus.it
Centro Cuore Columbus
Milan, Italy
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
RELATED ARTICLES
Thrombosis After Implantation of Drug-Eluting Stents
Emmanuel Marret, Jean-Phillipe Collet, Pierre Albaladejo, and Gilles Montalescot
JAMA. 2006;295(1):36.
EXTRACT
| FULL TEXT
Incidence, Predictors, and Outcome of Thrombosis After Successful Implantation of Drug-Eluting Stents
Ioannis Iakovou, Thomas Schmidt, Erminio Bonizzoni, Lei Ge, Giuseppe M. Sangiorgi, Goran Stankovic, Flavio Airoldi, Alaide Chieffo, Matteo Montorfano, Mauro Carlino, Iassen Michev, Nicola Corvaja, Carlo Briguori, Ulrich Gerckens, Eberhard Grube, and Antonio Colombo
JAMA. 2005;293(17):2126-2130.
ABSTRACT
| FULL TEXT
|
