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by Tak W. Mak and Mary E. Saunders, includes CD-ROM, 1194 pp, with illus, $139.95, ISBN 0-12-088451-8, Philadelphia, Pa, Elsevier, 2006.

JAMA. 2006;295:1456-1457.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Appreciation of the role of the immune system in health and disease has accelerated rapidly in recent years. In the early days, study of immunity focused on microbial infections, vaccines, and anaphylaxis. As biomedical research advanced, the relevance of the immune response extended to clinical fields such as cancer, autoimmunity, transplantation, and AIDS. The disciplines of diagnostic immunology, immunomodulation, immunotherapeutics, and immunogenetics have recently emerged.

There are numerous textbooks on basic immunology and clinical immunology, some of which have been published in updated form for 40 years. Into this crowded field comes a new book, The Immune Response: Basic and Clinical Principles. How does it stack up?

The Immune Response is a single-volume hardcover text of 1194 pages. Most textbooks this size are written by 50 to 100 chapter authors and edited by a small team of editors. However, the chapters of The Immune Response were authored or coauthored . . . [Full Text of this Article]

James T. Li, MD, Reviewer
Mayo Clinic College of Medicine
Rochester, Minn
li.james@mayo.edu