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To the Editor: Dr Winkelmayer and colleagues¹ reported that habitual coffee consumption was not associated with increased risk of hypertension in a 12-year follow-up of the Nurses' Health Studies I and II. This finding is in keeping with the results of several previous studies, which showed that habitual coffee drinking influences blood pressure only marginally.^2-3

However, coffee and cigarettes have been shown to have an interactive effect on blood pressure under laboratory conditions.⁴ Drinking coffee had no significant effect on blood pressure, whereas smoking a single cigarette elevated blood pressure for 15 minutes. However, when smoking and coffee were combined, there was a 10 mm Hg increase in blood pressure that was still present 2 hours later. In a population study, daytime blood pressure was only marginally affected by coffee drinking.³ However, there was a significant interaction between smoking and coffee use on ambulatory blood pressure. Average daytime blood pressure . . . [Full Text of this Article]

Paolo Palatini, MD
palatini@unipd.it
University of Padova
Padova, Italy

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