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Genomics Proving a Powerful Tool for Mapping the Landscape of the Brain
Bridget M. Kuehn
JAMA. 2006;295:145-148.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Two ongoing, large-scale projects may help better define neuroanatomy by using gene expression to classify the regions and cells of the mouse brain.
The brain in many ways remains uncharted. Scientists estimate there are about 1000 different types of neurons, many as yet undefined, and there is ongoing debate about the boundaries of anatomic regions. But the emergence of genomics has provided a basis for the development of new tools for systematically mapping all the genes, and regions of the brain.
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The Allen Brain Atlas project, an effort to map the thousands of genes expressed in the mouse brain, is making the data available on the Web, including 2-dimensional images depicting gene expression in various regions of the brain. (Photo credit: The Allen Institute for Brain Science)
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Two such projects have already resulted in data that are available online to the public. The Allen Brain Atlas project, . . . [Full Text of this Article] A DIFFERENT MODEL
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