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Adding to the Evidence

Timothy R. Church, PhD

JAMA. 2006;295:2411-2412.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Two articles^1-2 in this issue of JAMA address aspects of the well-established benefits of colorectal cancer screening. The first study, by Singh et al,¹ attempts to estimate the effect of the interval between colonoscopic screening in an asymptomatic population on the benefits of the procedure. Although national guidelines recommend colonoscopy every 10 years,^3-5 this interval is not based on any direct, systematic evidence, but rather rests on anecdotal evidence and informed clinical judgment. The second study, by Lin et al,² compares the findings of colonoscopy in an asymptomatic population 80 years and older with findings in a younger population aged 50 to 54 years. The practice of when to stop screening elderly individuals varies within the United States and throughout the world because little evidence on age-specific efficacy exists. These 2 studies address 2 very important and unresolved questions in colorectal cancer screening by colonoscopy, and . . . [Full Text of this Article]

Author Affiliation: Division of Environmental Health Sciences, University of Minnesota School of Public Health, Minneapolis.

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