 |
|
Fluoxetine Treatment of Anorexia Nervosa
Important but Disappointing Results
Scott J. Crow, MD
JAMA. 2006;295:2659-2660.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
Anorexia nervosa is a severe, treatment-resistant illness primarily affecting women. It has one of the highest all-cause mortalities, and the highest suicide rate of any psychiatric illness.1-2 Restriction of food intake, refusal to maintain adequate body weight, and disturbed thinking about food, weight, and body image are hallmarks of this illness. A prominent associated feature is profound ambivalence about therapeutic efforts (whether nutritional, psychological, or pharmacological) aimed at weight restoration. In addition to the classic pattern of extreme food restriction, a subset of patients also report binge eating and purging behaviors (the "binge-purge subtype"). Co-occurring psychopathology is common, especially depression, obsessive-compulsive disorder, and other anxiety disorders.3
In severely malnourished patients with anorexia nervosa, nutritional rehabilitation with weight restoration is the cornerstone of treatment, and this intervention often requires hospitalization. Psychotherapy is also a regular part of treatment. Preliminary evidence supports use of a specific family-based psychotherapy . . . [Full Text of this Article]
Author Affiliation: University of Minnesota, Minneapolis.
RELATED ARTICLE
Fluoxetine After Weight Restoration in Anorexia Nervosa: A Randomized Controlled Trial
B. Timothy Walsh, Allan S. Kaplan, Evelyn Attia, Marion Olmsted, Michael Parides, Jacqueline C. Carter, Kathleen M. Pike, Michael J. Devlin, Blake Woodside, Christina A. Roberto, and Wendi Rockert
JAMA. 2006;295(22):2605-2612.
ABSTRACT
| FULL TEXT
|
