 |
|
Critically Ill Patients and Acute Renal Failure
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
To the Editor: The multinational study of acute renal failure (ARF) in critically ill patients by Dr Uchino and colleagues1 supports findings of a number of smaller studies.2-4 However, we would like to raise some questions about the results. First, enrollment of patients younger than 18 years is unusual in adult trials, and this decision may have had an impact on cohort mortality. Second, general predictive scores (Acute Physiology and Chronic Health Evaluation [APACHE] II, Sequential Organ Failure Assessment [SOFA], Simplified Acute Physiology Score [SAPS] II) do not perform well when applied to patients with ARF.4 Applying a specific predictive score2-3 to such a variety of practices and diversity of populations might have been more valuable.
Third, requiring renal replacement therapy (RRT) is definitely an indication of severity of illness in patients receiving intensive care for ARF, yet 27.5% of the cohort did not undergo dialysis. The mortality rate for . . . [Full Text of this Article]
Domingos O. d’Avila, MD, PhD
dominavila@pucrs.br
Carlos E. Poli de Figueiredo, MD, PhD
Programa de Pós-Graduação em Medicina e Ciências da Saúde (Nefrologia)
IPB/HSL/Faculdade de Medicina–PUCRS
Porto Alegre, Brazil
RELATED ARTICLES
Acute Renal Failure in Critically Ill Patients: A Multinational, Multicenter Study
, , , , , , , , , , , , , and
JAMA. ;294():813-818.
FULL TEXT
Critically Ill Patients and Acute Renal Failure
JAMA. ;295():624-624.
FULL TEXT
Critically Ill Patients and Acute Renal Failure--Reply
, , and
JAMA. ;295():624-625.
FULL TEXT
|
