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Dietary Modification and CVD Prevention
A Matter of Fat
Cheryl A. M. Anderson, PhD, MPH;
Lawrence J. Appel, MD, MPH
JAMA. 2006;295:693-695.
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Cardiovascular disease (CVD) is the leading cause of mortality in women in the United States and throughout most of the world.1-2 The contemporary approach to prevention of CVD includes lifestyle modification for all adults and medical therapy for those with CVD risk factors (hypertension, hypercholesterolemia, or diabetes).3 The report in this issue of JAMA by Howard et al from the Women's Health Initiative (WHI)4 is timely, given recent major initiatives that focus on CVD prevention in women.3
In 1991, the National Institutes of Health launched the WHI research program, a series of major clinical trials and large observational studies that addressed the most common causes of death and disability in postmenopausal womenCVD, cancer, and osteoporosis.5 The WHI research program involved extraordinary commitment and effort on the part of numerous investigators and staff members and more than 100 000 participants. Their . . . [Full Text of this Article]
Author Affiliations: Johns Hopkins University Bloomberg School of Public Health (Drs Anderson and Appel) and School of Medicine (Dr Appel), Baltimore, Md.
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Low-Fat Dietary Pattern and Risk of Cardiovascular Disease: The Women's Health Initiative Randomized Controlled Dietary Modification Trial
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JAMA. 2006;295(6):655-666.
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