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Granulocyte-Colony Stimulating Factor
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Granulocyte colony-stimulating factor (G-CSF) is a blood growth factor (special proteins produced by the body) that stimulates the bone marrow to produce more infection-fighting white blood cells called neutrophils. Granulocyte colony-stimulating factor causes cells from the bone marrow to become mature and activated. These cells then circulate into the bloodstream. Other types of growth factors called granulocyte-macrophage colony-stimulating factors affect the growth of other types of white blood cells along with neutrophils.
Granulocyte colony-stimulating factor is produced naturally by the body and is also available as an injection for patients with low white blood cell counts at risk of infection. The March 1, 2006, issue of JAMA includes an article about the experimental use of G-CSF in patients who have had a myocardial infarction (heart attack).
USES OF G-CSF
Chemotherapy (drugs used to kill cancer cells) can damage rapidly dividing normal cells, such as the hair follicle cells that grow . . . [Full Text of this Article]
Erin Brender, MD, Writer;
Cassio Lynm, MA, Illustrator;
Richard M. Glass, MD, Editor
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