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Sickle Cell and Thalassemia Pioneer

Tracy Hampton, PhD

JAMA. 2006;295:991.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Sickle cell disease and thalassemia, inherited disorders of hemoglobin, constitute the most common genetic diseases in the world, and aggressive lifelong treatments are required for managing the anemia and other painful complications that accompany them.

Yuet Wai Kan, MD, of the University of California, San Francisco, has led the way in the study and treatment of these diseases. In the mid-1970s, he discovered the genetic mutations in the - and -globin genes that cause - and -thalassemia, respectively. He also ushered in the era of genetic testing for diseases by discovering DNA analysis techniques for tracing the transmission of disease-causing genes in families.

Yuet Wai Kan, MD (Photo credit: Yuet Wai Kan, MD/Anthony Buckley & Constantine)

Kan has won many awards, most notably the Albert Lasker Clinical Medical Research Award in 1991. Today he continues to make contributions with his research on potential treatments for these diseases. . . . [Full Text of this Article]

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