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Tracy Hampton, PhD

JAMA. 2006;296:1573-1575.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

While experts have been sounding the warning bell about obesity's potential links to increased risks for such conditions as type 2 diabetes, cardiovascular disease, and even cancer, many of the molecular details of these associations have remained unclear.

Researchers are studying the molecular details of how fat cells and the molecules they produce influence the development of obesity, heart disease, and other conditions. (Photo credit: David M. Phillips/www.sciencesource.com)

Now researchers homing in on some of the mechanisms involved are finding that molecules called adipokines secreted by adipose tissue may play a major role. One adipokine, adiponectin, is of particular interest because it regulates insulin sensitivity and lipid oxidation and may lower the risk of myocardial infarction.

"Adiponectin is a good guy," said Guenther Boden, MD, of Temple University Hospital, in Philadelphia. "It seems to be something that really has beneficial effects on insulin action and . . . [Full Text of this Article]

ACTIONS OF ADIPOSE



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