This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (2)  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in JAMA  Topic Collections  • Stroke  • Rehabilitation Medicine  • Prognosis/ Outcomes  • Alert me on articles by topic  Social Bookmarking   What's this?

Andreas R. Luft, MD; Daniel F. Hanley, MD

JAMA. 2006;296:2141-2143.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Stroke produces well-known motor and cognitive impairment and high levels of disability. Currently used stroke rehabilitation treatments generally are based on empirical approaches rather than scientifically validated therapies.^1-3 A wide variety of poorly standardized and unevaluated traditional treatments aim to recondition spinal or muscular targets to prevent⁴ or accommodate⁵ impaired motor control. The results of the EXCITE (Extremity Constraint Induced Therapy Evaluation) trial reported by Wolf and colleagues⁶ in this issue of JAMA contribute to a new understanding of how to approach disability in stroke survivors. A careful look at this trial and its background opens new directions for clinical care, stroke recovery, rehabilitation care delivery, and research. Such new directions are of utmost importance for stroke survivors who hope to reacquire abilities lost after ischemic brain injury.

The EXCITE trial is the first multisite randomized study to demonstrate the efficacy of . . . [Full Text of this Article]

Affiliations: Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany (Dr Luft); Division of Brain Injury Outcomes, Department of Neurology, Johns Hopkins University (Drs Luft and Hanley), Department of Neurology (Dr Luft) and Department of Medicine, Division of Gerontology (Dr Hanley), University of Maryland School of Medicine, and Department of Veterans Affairs, Baltimore VA Medical Center Geriatric Research, Education and Clinical Center (Drs Luft and Hanley), Baltimore, Md.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED ARTICLE

Effect of Constraint-Induced Movement Therapy on Upper Extremity Function 3 to 9 Months After Stroke: The EXCITE Randomized Clinical Trial
Steven L. Wolf, Carolee J. Winstein, J. Philip Miller, Edward Taub, Gitendra Uswatte, David Morris, Carol Giuliani, Kathye E. Light, Deborah Nichols-Larsen, and for the EXCITE Investigators
JAMA. 2006;296(17):2095-2104.
ABSTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Constraint-Induced Therapy Versus Dose-Matched Control Intervention to Improve Motor Ability, Basic/Extended Daily Functions, and Quality of Life in Stroke
Lin et al.
Neurorehabil Neural Repair 2009;23:160-165.
ABSTRACT  

Revisiting Constraint-Induced Movement Therapy: Are We Too Smitten With the Mitten? Is All Nonuse "Learned"? and Other Quandaries
Wolf
ptjournal 2007;87:1212-1223.
ABSTRACT | FULL TEXT