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  Vol. 296 No. 21, December 6, 2006 TABLE OF CONTENTS
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Search Is On for Cells That Repair Heart

Tracy Hampton, PhD

JAMA. 2006;296:2541.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

New York—While some organs such as the liver have impressive regenerative properties, the heart has very limited self-healing capacities. In an attempt to boost heart regeneration, scientists are studying potential therapies that could replace heart tissue that might otherwise be left permanently damaged following injury. At the New York Stem Cell Foundation's recent Translational Stem Cell Research Conference, scientists discussed the progress and pitfalls of these studies.

TESTING ADULT CELLS

Many researchers are testing various adult cell types—such as bone marrow cells, skeletal myoblasts, and adipocytes—for their potential to "transdifferentiate" into cardiac muscle and to heal the heart after myocardial infarction, ischemic heart failure, and other types of heart disease. The hope is that by injecting such cells into the right environment in the heart, they will be coaxed to become heart muscle cells.

"We have identified a number of stem cell sources that are in more than 40 . . . [Full Text of this Article]



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