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Bridget M. Kuehn

JAMA. 2006;296:2790.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

A variety of lifestyle factors have been associated with a reduced risk of developing cancer, but scientists know little about how these protective benefits are modulated by an individual's sex, ethnicity, or other lifestyle factors. Now, results from studies on the potential cancer-protecting benefits of exercise and aspirin use, presented at American Association for Cancer Research's Frontiers in Cancer Prevention Research meeting last month are helping to close those gaps in knowledge.

Many large population studies have suggested that individuals who are physically active have a lower risk of colon cancer, with the strongest effects being seen in men. In the first randomized placebo-controlled study of how exercise effects the colon at the molecular level, Kristin Campbell, PhD, a postdoctoral fellow at the Fred Hutchinson Cancer Research Center in Seattle, and colleagues, randomly assigned 101 men and 98 women to either continue their low-activity lifestyle or to engage . . . [Full Text of this Article]

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