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edited by Robert W. Colman, Victor J. Marder, Alexander W. Clowes, James N. George, and Samuel Z. Goldhaber, 5th ed, 1827 pp, with illus, $299, ISBN 0-7817-4996-4, Philadelphia, Pa, Lippincott Williams & Wilkins, 2006.

JAMA. 2006;296:338.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The accelerated pace of recent advances in this area of medicine, so critical to improving patient care, prompts the timely publication of the fifth edition of Hemostasis and Thrombosis. Remarkably, the first edition (1982) was less than 100 pages shorter yet contained 81 chapters, compared with 123 in the new edition. The editors have efficiently organized the content, which is presented in a comprehensive and concise manner. The contributors are among the foremost authorities in their fields.

Part 1 is devoted to molecular components of the coagulation cascade and associated entities, including platelets and endothelium. The first chapters present basic principles of hemostasis and thrombosis, beginning with a comprehensive overview. Each of the next 57 chapters deals with a specific molecular component of the hemostatic system, including its genetic, biochemical, and physiologic characteristics. Eight of these chapters pertain to the fibrinolytic system, including the recently described thrombin activatable fibrinolysis inhibitor, . . . [Full Text of this Article]

Harry L. Messmore, MD, Reviewer
Loyola University Medical Center
Hines Veterans Hospital
Hines, Ill
hlmehd64@aol.com

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