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Physical Activity, Body Mass Index, and Cardiovascular Biomarkers in Women
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To the Editor: In their study of the association of physical activity and body mass index (BMI) with cardiovascular biomarkersin women, Dr Mora and colleagues1 concluded that high BMI was more strongly related to adverse cardiovascular biomarkers than was physical inactivity. This was based on the stronger association between high BMI and these biomarkers than physical inactivity and biomarkers: BMI had higher odds ratios (OR) than physical inactivity.
I believe that this conclusion is not warranted. The OR contains the same information as the logistic regression coefficient or the probability.2 Menard states that "the OR cannot take the place of a standardized logistic regression coefficient for valuating the strength of the influences of the independent variables on the dependent variable, relative to one another." The strength of each independent variable cannot be judged based on the magnitude of the OR, so that a larger OR for one independent variable might . . . [Full Text of this Article]
Huai Yong Cheng, MD, MPH
hyc2105@columbia.edu
Department of Medicine
Columbia University Medical Center
New York, NY
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