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Bridget M. Kuehn

JAMA. 2007;297:1419-1421.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Scientists using advanced brain imaging and genetic testing to probe the physiological basis of addiction are gleaning new insights into these disorders and how to treat them.

A symposium sponsored by Brookhaven National Laboratory (Upton, NY), held in conjunction with the American Association for the Advancement of Science's annual meeting in San Francisco in February, highlighted several advances in addiction science made over the past year. Researchers presented findings from brain imaging studies revealing the importance of memory and drug-related cues in addiction, the role of monoamine oxidase–inhibiting compounds in cigarette smoking, the damage to inhibitory controls caused by methamphetamine use, as well as results from studies suggesting that genomics could be used to better tailor addiction therapies.

Positron emission tomography scans reveal that low activity levels in the cerebral cortex, as measured by metabolism of radiolabeled glucose, are positively correlated (yellow areas) with depression in individuals . . . [Full Text of this Article]

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