This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (5)  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Topic Collections  • Neurology  • Alzheimer Disease  • Anesthesia  • Alert me on articles by topic  Social Bookmarking   What's this?

Bridget M. Kuehn

JAMA. 2007;297:1760.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Some commonly used inhaled anesthetics may cause brain damage that accelerates the onset of Alzheimer disease, according to recent findings from two separate groups of scientists.

For more than a decade, physicians and scientists have searched for clues to why some people experience cognitive dysfunction after undergoing anesthesia and surgery (Brewer K et al. Anesthesia exposure as a possible risk factor for cognitive decline in the elderly. In: Alzheimer's Disease. Paris: Serdi Publishing Company;1996:161-171). Some studies also have suggested that age of onset of Alzheimer disease may be associated with previous anesthetic exposure during surgery, although the results from these small studies were not significant (Bohnen N et al. Int J Neurosci. 1994;77:181-185; Gasparini M et al. Neurol Sci. 2002;23:11-14; Lee TA et al. J Alzheimers Dis. 2005:7:319-324). Now, scientists are beginning to tease out the mechanisms behind anesthesia's ill effects on the . . . [Full Text of this Article]

MORE PLAQUES



CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?