Pharmacy Care Programs and Clinical Outcomes—Reply
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In Reply: We agree with Dr Mariotto that many diverse factors contribute to hypertension and success in its management and that the evaluation of such potential confounders is an important step in the evaluation of clinical trials. The intervention used in the Federal Study of Adherence to Medications in the Elderly focused on adherence to medications that have known efficacy in the treatment of hypertension and hyperlipidemia. No data were collected on factors such as physical activity or diet, so we cannot present a comparison between the study groups or adjust for any differences.
Regarding the generalizability of our findings to other populations, the participant characteristics we described in Table 1 suggest the types of patients for whom our results are most directly applicable. We agree that data from clinical trial populations are most appropriately translated to clinical care populations when both are closely matched on relevant variables.
Financial Disclosures: . . . [Full Text of this Article]
Allen J. Taylor, MD
allen.taylor@na.amedd.army.mil
Jeannie K. Lee, PharmD;
Karen A. Grace, PharmD
Walter Reed Army Medical Center
Washington, DC
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