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Antibiotic-Resistant Plague
Tracy Hampton, PhD
JAMA. 2007;297:1870.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Certain circular DNA molecules called plasmids that confer antibiotic resistance in bacteria found in meat and poultry also have been discovered in the plague bacillus Yersinia pestis, according to a research team led by investigators at the Institute for Genomic Research, in Rockville, Md (Welch TJ et al. PLoS ONE. doi:10.1371/journal.pone.0000309 [published online March 21, 2007]).
While the plasmid that confers antibiotic resistance has been associated with only 1 case of the bubonic plague in Madagascar, it is broadly disseminated among bacteria such as Salmonella enterica and Escherichia coli that affect US livestock.
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Circular DNA molecules that confer antibiotic resistance in bacteria have been found in the plague bacillus, Yersinia pestis. (Photo credit: Oregon State Public Health Laboratory/CDC)
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"This reservoir of mobile resistance determinants has the potential to disseminate to Y pestis and other human and zoonotic bacterial pathogens and therefore represents a significant . . . [Full Text of this Article]
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