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  Vol. 297 No. 17, May 2, 2007 TABLE OF CONTENTS
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Antibiotic-Resistant Plague

Tracy Hampton, PhD

JAMA. 2007;297:1870.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Certain circular DNA molecules called plasmids that confer antibiotic resistance in bacteria found in meat and poultry also have been discovered in the plague bacillus Yersinia pestis, according to a research team led by investigators at the Institute for Genomic Research, in Rockville, Md (Welch TJ et al. PLoS ONE. doi:10.1371/journal.pone.0000309 [published online March 21, 2007]).

While the plasmid that confers antibiotic resistance has been associated with only 1 case of the bubonic plague in Madagascar, it is broadly disseminated among bacteria such as Salmonella enterica and Escherichia coli that affect US livestock.


Figure 70003FA
Circular DNA molecules that confer antibiotic resistance in bacteria have been found in the plague bacillus, Yersinia pestis. (Photo credit: Oregon State Public Health Laboratory/CDC)

"This reservoir of mobile resistance determinants has the potential to disseminate to Y pestis and other human and zoonotic bacterial pathogens and therefore represents a significant . . . [Full Text of this Article]



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