 |
|
Does Clopidogrel Each Day Keep Stent Thrombosis Away?
Dean J. Kereiakes, MD
JAMA. 2007;297:209-211.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
New medicines and new methods of cure always work miracles . . . for a while.
William Heberden, MD
The polymer-based elution of antiproliferative medications from a metal stent prosthesis has been demonstrated to suppress neointimal proliferative response to stent-vessel injury and to reduce consequent late arterial lumen loss and restenosis. In randomized controlled trials, drug-eluting stents compared with bare-metal stents caused a 70% to 80% reduction in binary (>50%) angiographic restenosis and a 50% to 70% reduction in repeat target lesion or vessel revascularization.1-2 Furthermore, comprehensive follow-up to 1 year demonstrated no evidence for any excess in the incidence of death, myocardial infarction (MI), or stent thrombosis for either treatment strategy.3-4 Thus, based on pivotal clinical trial evidence for both the relative safety and efficacy of drug-eluting stents, the US Food and Drug Administration approved both Cypher, the sirolimus-eluting stent, in 2002, as well as TAXUS, the paclitaxel-eluting . . . [Full Text of this Article]
Author Affiliations: The Heart Center of Greater Cincinnati and The Lindner Research Center at The Christ Hospital, Cincinnati, Ohio; and The Ohio State University, Columbus.
RELATED ARTICLE
Clopidogrel Use and Long-term Clinical Outcomes After Drug-Eluting Stent Implantation
Eric L. Eisenstein, Kevin J. Anstrom, David F. Kong, Linda K. Shaw, Robert H. Tuttle, Daniel B. Mark, Judith M. Kramer, Robert A. Harrington, David B. Matchar, David E. Kandzari, Eric D. Peterson, Kevin A. Schulman, and Robert M. Califf
JAMA. 2007;297(2):159-168.
ABSTRACT
| FULL TEXT
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Thrombosis and Drug-Eluting Stents: An Objective Appraisal
Holmes et al.
J Am Coll Cardiol 2007;50:109-118.
ABSTRACT
| FULL TEXT
Patients with drug eluting stents do better on long term clopidogrel
BMJ 2007;334:119-119.
FULL TEXT
|
