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Green Tea Consumption and Mortality in Japan
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To the Editor: The study of green tea consumption and mortality by Dr Kuriyama and colleagues1 concluded that green tea consumption is associated with reduced mortality due to all causes and due to cardiovascular disease but not with reduced mortality due to cancer. I believe that these conclusions can only be made for consumption of 100 to 500 mL/d of the green teas purchased in northeastern Japan.
Pharmacodynamic data from the National Cancer Institute indicate that for a 70-kg person, consumption of 800 mL (4 cups) of green tea that contains 710 µg/mL of (–)–epigallocatechin gallate would be required to be comparable with the lowest effective anticancer dose in animal model studies.2 There is evidence of green tea as a cancer preventive for humans in other parts of Japan where quality green teas, "typical" as defined by the National Cancer Institute, are traditionally consumed.3-4 Because amount of tea consumption and . . . [Full Text of this Article]
Sin Hang Lee, MD
sinhang.lee@milfordhospital.org
Department of Pathology
Milford Hospital
Milford, Conn
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