This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in JAMA  Topic Collections  • Genetic Disorders  • Women's Health, Other  • Prognosis/ Outcomes  • Cardiovascular Disease/ Myocardial Infarction  • Alert me on articles by topic

Roger S. Blumenthal, MD; Erin D. Michos, MD; Khurram Nasir, MD, MPH

JAMA. 2007;297:641-643.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Coronary heart disease (CHD) is the leading cause of death for women and men in the United States. Because half of first major coronary events occur in asymptomatic individuals,¹ clinicians who want to implement appropriate primary prevention therapy must be able to accurately identify "at risk" individuals. The third National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP-III) guidelines² recommend that all adults should undergo an office-based assessment to evaluate risk of a CHD event based on the Framingham risk score. This prediction algorithm incorporates age, levels of total cholesterol, and high-density lipoprotein cholesterol (HDL-C), smoking status, and systolic blood pressure to estimate a 10-year risk for developing a myocardial infarction or death due to CHD.²

Three levels of risk (low, intermediate, and high) are identified. The 2001 NCEP ATP-III guidelines define intermediate risk as a 10% . . . [Full Text of this Article]

Author Affiliations: Ciccarone Preventive Cardiology Center, Johns Hopkins University, School of Medicine, Baltimore, Md (Drs Blumenthal and Michos) and Massachusetts General Hospital Cardiac MRI PET CT Program, Boston (Dr Nasir).

RELATED ARTICLE

Development and Validation of Improved Algorithms for the Assessment of Global Cardiovascular Risk in Women: The Reynolds Risk Score
Paul M Ridker, Julie E. Buring, Nader Rifai, and Nancy R. Cook
JAMA. 2007;297(6):611-619.
ABSTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Depression and Ischemic Heart Disease Mortality: Evidence From the EPIC-Norfolk United Kingdom Prospective Cohort Study
Surtees et al.
Am. J. Psychiatry 2008;165:515-523.
ABSTRACT | FULL TEXT  

Total Coronary Artery Calcium Score Remains Preferred Metric to Refine Risk Prediction in Nearly All Patients
Bansal and Blumenthal
J Am Coll Cardiol Img 2008;1:70-72.
FULL TEXT  

A New Model for Predicting Cardiovascular Risk in Women?
Journal Watch Cardiology 2007;2007:1-1.
FULL TEXT