This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Related letter  • Related article  • Similar articles in JAMA  Topic Collections  • Tobacco  • Statistics and Research Methods  • Genetics, Other  • Alert me on articles by topic  Social Bookmarking   What's this?

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In Reply: In response to Dr Bierut and colleagues, the central motivation of our Commentary was not to curtail research funding, and we hope that a careful reading will dissuade others from this interpretation. Rather, we argued for wise use of public resources.¹ The relative or absolute amount of funding directed toward genetic studies of smoking behavior or its complications is not critical to the debate. Our goal is to encourage a thoughtful "step back" from current smoking-related genetic research to consider how such work interfaces with existing public health efforts in this arena.

We take issue with the suggestion that our call was solely for "results that have immediate clinical application." Certainly, research funders must place an appropriate priority on research likely to yield short-term benefits, and smoking-related genetic research is unlikely to meet this criterion. However, we noted other potential long-term benefits from such research: it might provide . . . [Full Text of this Article]

Chris Carlsten, MD, MPH
carlsten@u.washington.edu

Wylie Burke, MD, PhD
University of Washington
Seattle

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED LETTER

Genetic Research and Smoking Behavior
Laura Jean Bierut, Joseph F. Cubells, William G. Iacono, Ming D. Li, Pamela A. F. Madden, Elliot C. Nelson, Jonathan D. Pollock, Joni L. Rutter, Gary E. Swan, and Michael Vanyukov
JAMA. 2007;297(8):809.
EXTRACT | FULL TEXT  

RELATED ARTICLE

Potential for Genetics to Promote Public Health: Genetics Research on Smoking Suggests Caution About Expectations
Chris Carlsten and Wylie Burke
JAMA. 2006;296(20):2480-2482.
EXTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

The common obesity variant near MC4R gene is associated with higher intakes of total energy and dietary fat, weight change and diabetes risk in women
Qi et al.
Hum Mol Genet 2008;17:3502-3508.
ABSTRACT | FULL TEXT