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Extensively Drug-Resistant TuberculosisAn Isolation Order, Public Health Powers, and a Global Crisis
Howard Markel, MD, PhD;
Lawrence O. Gostin, JD;
David P. Fidler, JD
JAMA. 2007;298:83-86.
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Centuries after the formal creation of quarantine, the practice continues to evoke concern when implemented to halt the spread of dangerous microbes. Witness the controversy generated by US citizen Andrew Speaker, whom the US Centers for Disease Control and Prevention (CDC) detained and isolated because he was diagnosed with pulmonary disease caused by extensively drug-resistant tuberculosis (XDR-TB). Speaker's case made compelling news, but it also raised questions about the emergence of XDR-TB, the adequacy of public health powers in the United States, and the international dimensions of the XDR-TB threat.
The Recent Encounter With XDR-TB
According to media reports,1-3 congressional testimony,4 and official reports,5 physicians diagnosed Speaker with pulmonary TB in March 2007. He was prescribed a regimen of standard anti-TB medications. Susceptibility testing determined that Speaker's TB was multidrug resistant, which prompted county public health authorities to advise Speaker orally on May . . . [Full Text of this Article] The Complexity of Quarantine Law State Quarantine Authority Federal Quarantine Authority Proposed Revisions to the Federal Quarantine Regulations Travel Restrictions on Persons Leaving the United States Extrajurisdictional Application of US Public Health Law Screening for Public Health Threats at US Borders XDR-TB and the New International Health Regulations
Author Affiliations: Center for the History of Medicine, University of Michigan, Ann Arbor (Dr Markel); ONeill Institute for National and Global Health Law, Georgetown University Law Center, Washington, DC (Mr Gostin); and Indiana University School of Law, Bloomington (Mr Fidler).
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