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Parthenogenetic Stem Cells
Tracy Hampton, PhD
JAMA. 2007;298:1152.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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The Korean embryonic stem cell line that was once touted as the first to be created through somatic cell nuclear transfer (the replacement of an egg's DNA with the DNA from a cell in the body) originated from parthenogenesis, an entirely different process, a recent investigation from Children's Hospital Boston and the Harvard Stem Cell Institute reveals (Kim K et al. Cell Stem Cell. doi:10.1016/j.stem .2007.07.001 [published online ahead of print August 2, 2007]). In parthenogenesis (so-called virgin birth), all the DNA from the developing organism comes from the unfertilized egg.
The research from Korea (Hwang WS et al. Science. 2004;303[5664]:1669-1674), initially lauded as a groundbreaking achievement, was retracted amid evidence that the scientists had falsified their data, but the derivation of the cell line was never fully resolved.
Parthenogenesis and somatic cell nuclear transfer can be used to generate embryonic stem cells that are . . . [Full Text of this Article]
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