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Health Outcomes in Long-term Survivors of Childhood Cancer—Reply
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In Reply: Drs Kakaki and Theleritis describe the effect of psychological trauma in children exposed to chronic illness, especially life-threatening illness. They state that for these children certain preventive measures should be implemented.
In our study, 177 of 3751 adverse events (4.8%) were categorized as emotional problems. Almost 12% of these emotional adverse events were severe, life-threatening, or disabling. However, we do not know if those problems were the results of psychological trauma. Furthermore, we were not able to compare the prevalence of emotional adverse events in our survivors of childhood cancer with that in a control group without a history of cancer.
The psychosocial consequences of having childhood cancer and of being a survivor of childhood cancer are complex. Previous studies have shown varying results that are influenced by differences in study populations, psychometric instruments, and definitions of outcomes of interest. Some studies have suggested that among survivors of . . . [Full Text of this Article]
Leontien C. M. Kremer, MD, PhD;
Mathilde C. Cardous-Ubbink, MSc
Department of Pediatric Oncology
Emma Children's Hospital/Academic Medical Center
Amsterdam, the Netherlands
Maud M. Geenen, MD
Department of Medical Oncology
Academic Medical Center
Amsterdam
Flora E. van Leeuwen, PhD
Netherlands Cancer Institute
Amsterdam
Huib N. Caron, MD, PhD
h.n.caron@amc.uva.nl
Department of Pediatric Oncology
Emma Children's Hospital/Academic Medical Center
RELATED LETTER
Health Outcomes in Long-term Survivors of Childhood Cancer
Marina Kakaki and Christos Theleritis
JAMA. 2007;298(14):1635.
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