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Leveraging University Research to Advance Global Health
Dave A. Chokshi, MSc;
Rahul Rajkumar, MD, JD
JAMA. 2007;298:1934-1936.
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The world's destitute sick face a perilous disadvantage in accessing essential medicines. The crisis stems from 2 related problems. First, for the billion people affected by neglected diseases such as trypanosomiasis and cholera, few safe and effective treatment options exist. Because these neglected diseases predominantly affect the poor, they attract little research and development funding, leading to a paucity of therapies.1 Second, for other diseases, several interlinked factors impede access to medicines that do exist: high prices, underfunded and uncoordinated health care systems, and drug formulations ill-suited to resource-poor settings.
Generic competition has lowered the price of antiretroviral therapy for human immunodeficiency virus (HIV) from more than $15 000 per patient-year 6 years ago to $99 today.2 Concomitant with this decrease in prices has been an increase in funding and political will to address the HIV/AIDS pandemic. This has shifted the debate from . . . [Full Text of this Article] The Role of Universities
Author Affiliations: University of Pennsylvania School of Medicine, Philadelphia (Mr Chokshi); and Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts (Dr Rajkumar).
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