You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT JAMA
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 298 No. 17, November 7, 2007 TABLE OF CONTENTS
  JAMA
  •  Online Features
  Medical News & Perspectives
 This Article
 •Full text
 •PDF
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citing articles on ISI (1)
 •Contact me when this article is cited
 Related Content
 •Similar articles in JAMA
 Topic Collections
 •Drug Therapy, Other
 •Renal Diseases
 •Dialysis
 •Randomized Controlled Trial
 •Alert me on articles by topic

Study Probes Best Choice of Drug to Reduce Phosphate in Patients on Dialysis

Mike Mitka

JAMA. 2007;298(17):1995-1996.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

A costly and widely used medication for patients on hemodialysis is no better at reducing mortality than lower-cost alternatives, according to the findings of a new study.

In the largest prospective randomized study to date comparing patients on hemodialysis who were given sevelamer hydrochloride (Renagel, Genzyme Corporation, Cambridge, Mass) or a calcium-based binder to treat hyperphosphatemia, the Dialysis Clinical Outcomes Revisited (DCOR) trial, researchers found that all-cause mortality was the same in the group taking sevelamer (267 deaths) and the group taking a calcium-based binder (275 deaths) (Suki WN et al. Kidney Int. doi:10.1038/sj.ki.5002466 [published online ahead of print August 29, 2007]).


Figure 70111FA
Maintaining appropriate levels of phosphate is important for patients on hemodialysis, but the best way to do so remains open to debate. (Photo credit: AJPhoto/www.sciencesource.com)

However, in a prespecified secondary analysis of the trial (which was sponsored by Genzyme), the researchers did find . . . [Full Text of this Article]

GETTING RID OF PHOSPHATE







HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 2007 American Medical Association. All Rights Reserved.