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To the Editor: Dr Bansal and colleagues¹ observed that nonfasting triglyceride levels were more predictive of future cardiovascular risk than fasting triglyceride levels in healthy women. Studies of postprandial lipemia have shown a strong dependence of postprandial triglyceride levels on the level of fasting triglycerides.² Postprandial triglyceride concentration can be viewed as incorporating to some degree the fasting level as well; it effectively constitutes a composite index of lipemia of both the fasting and nonfasting states.

Given that most of each day is spent in a postprandial state, this index may more closely reflect the atherogenic burden conferred by triglyceride levels over time. Therefore, although a postprandial triglyceride measurement seems more informative in terms of risk, it does not directly follow that postprandial triglyceride levels are more atherogenic than fasting ones, only that they are atherogenic. For the relative atherogenicity of fasting vs nonfasting triglyceride levels to be examined, studies . . . [Full Text of this Article]

Konstantinos Tsarpalis, MB BChir, MA
ktsarpalis@yahoo.gr
Imperial College London
London, England

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