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Bridget M. Kuehn

JAMA. 2007;298(8):849-851.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The international public health community has long hoped for a vaccine that could prevent the more than 1 million deaths that occur each year from malaria infections. However, a variety of factors—including the complexity of the malarial parasite's life cycle, a lack of sufficient funding, and difficulties associated with conducting research in the developing countries that are hardest hit—have stymied progress.

Now, scientific developments and a renewed commitment to cooperation among researchers and funding organizations are helping to bring scientists closer to creating a viable malaria vaccine.

A multinational "roadmap" and new molecular insights into malaria are helping scientists working to develop a vaccine. (Photo credit: Malaria Vaccine Funders Group/Photo inset: William E Collins/CDC)

Scientists are probing the molecular basis of malaria infections and of immunity. With new insights into why previous clinical trials of candidate vaccines may have been disappointing, research teams are testing several distinct . . . [Full Text of this Article]

A NEW MODEL