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Evaluation of Suspected Pulmonary Embolism During Pregnancy—Reply
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In Reply: Dr Siegel raises an interesting point about which consensus does not yet seem to have been reached. Although some studies have calculated less fetal radiation exposure using helical CT scanning than scintigraphic lung scanning,1 other studies indicate little difference between the 2 modalities or somewhat less radiation with scintigraphy when only a perfusion scan is done.2 Moreover, CT estimates used very specific parameters for scanning time, collimation, and cranial-caudal scan extent, which might not strictly apply in all clinical situations. Some experts, such as a majority of PIOPED II (Prospective Investigation of Pulmonary Embolism Diagnosis II) investigators, recommend pulmonary scintigraphy for diagnosis of pulmonary embolism in the setting of pregnancy3 while others now recommend CTPA.4
Computed tomographic technology is rapidly evolving, and clinicians must stay informed of developments that may alter their test selection. Moreover, consistent application of validated prediction rules for pretest probability of pulmonary embolism/deep vein . . . [Full Text of this Article]
Jeffrey Glassroth, MD
j-glassroth@northwestern.edu Department of Medicine Feinberg School of Medicine Northwestern University Chicago, Illinois
RELATED LETTER
Evaluation of Suspected Pulmonary Embolism During Pregnancy
Mark D. Siegel
JAMA. 2008;299(14):1665.
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