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Normal Range for Pulmonary Artery Systolic Pressure—Reply
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In Reply: We agree with Drs Gnecchi-Ruscone and Rigo that the range of normal for pulmonary artery systolic pressure is influenced by age and body weight. In the case of the individual presented in our Grand Rounds, the upper limit of normal for pulmonary artery systolic pressure, assuming an estimated right atrial pressure of 5 mm Hg, is approximately 30 mm Hg, given his age (younger than 49 years) and body mass index (less than 25 [calculated as weight in kilograms divided by height in meters squared]).1
In groups of individuals who are relatively young and nonobese, an upper limit of normal of 30 mm Hg for pulmonary artery systolic pressure (assuming a right atrial pressure of 5 mm Hg) is not too conservative. For example, in our cohort of patients with sickle cell disease followed up at the National Institutes of Health, the median age was 34 years and . . . [Full Text of this Article]
Roberto F. Machado, MD
robertom@nhlbi.nih.gov
Pulmonary and Vascular Medicine Branch
National Heart, Lung, and Blood Institute
National Institutes of Health
Bethesda, Maryland
Priscilla Y. Hsue, MD
Division of Cardiology
University of California, San Francisco
Christopher F. Barnett, MD, MPH
Critical Care Medicine Department
Clinical Center
National Institutes of Health
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ABSTRACT
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RELATED LETTER
Normal Range for Pulmonary Artery Systolic Pressure
Tomaso Gnecchi-Ruscone and Fausto Rigo
JAMA. 2008;299(17):2022.
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