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Edited by Debasis Bagchi and Harry G. Preuss
569 pp, $149.95
London, UK, CRC Press, 2007
ISBN-13: 978-0-8493-3802-1

JAMA. 2008;299(17):2092-2093.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

This book is not a casual read. It is an in-depth treatise on the epidemiology, pathophysiology, prevention, and treatment of a modern-day epidemic, obesity. It begins with a detailed review of the prevalence and health burden of obesity worldwide and how the current situation has developed over the past 4 decades. Section 2 deals with the pathophysiology of obesity and the effects of environmental estrogens and endocrine disruption by plastics and environmental chemicals. This section likewise deals with the relationship between obesity and cigarette smoking, appetite, energy balance, and disordered eating, as well as the roles of neurotransmitters, neurobiology, leptin, ghrelin, and genetics. Section 3 deals with obesity and chronic cardiovascular diseases, including the metabolic syndrome and type 2 diabetes. Sections 4 and 5 deal with the development of obesity drugs, with reviews of their safety and effectiveness. Section 6 is quite long and deals with natural, nutritional, and physical . . . [Full Text of this Article]

Marshall Godwin, MD, MSc, CCFP, Reviewer
Department of Family Medicine
Memorial University of Newfoundland
St John’s, Newfoundland, Canada
godwinm@mun.ca