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In Reply: I appreciate the comments by Dr Kaushik and colleagues as musculoskeletal concerns are not infrequently expressed by adults with cystic fibrosis. The described episodic arthralgia and cutaneous nodules have been particularly problematic in 3 of our approximately 200 adult patients and would be worthy of systematic study given the limited literature in this area.¹

Financial Disclosures: Dr Boyle reported consulting for Novartis and Gilead.

Michael P. Boyle, MD
mboyle@jhmi.edu
Division of Pulmonary and Critical Care Medicine
Johns Hopkins University School of Medicine
Baltimore, Maryland

1. Hodson ME. Vasculitis and arthropathy in cystic fibrosis. J R Soc Med. 1992;85(suppl 19):38-40. ISI | PUBMED

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2008;299(4):408.

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Joint Problems and Cystic Fibrosis
Prashant Kaushik, James H. Lampman, and Richa Kaushik
JAMA. 2008;299(4):408.
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