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Albert W. Wu, MD, MPH; Angela K. M. Lipshutz, MPH; Peter J. Pronovost, MD, PhD

JAMA. 2008;299(6):685-687.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Preventable mistakes are common in medicine. For example, at 1 hospital, a patient received patient-controlled analgesia (PCA), a combination of local anesthetic and narcotic. The medication was intended to be infused into the epidural space. Instead, a nurse inadvertently connected the tubing to an intravenous catheter, delivering potentially lethal anesthetic into the patient's bloodstream. What followed were the nurse's anguish and guilt and, almost as inevitably, the hospital's root cause analysis (RCA). In the last decade, this process has become the main way medicine investigates mistakes and tries to prevent future mistakes. But like many innovations in medicine, RCA has never been evaluated for effectiveness.

In the case mentioned above, the team identified flaws in the design of the epidural catheter, but thought that fixing those flaws was beyond their scope. Therefore, they made a . . . [Full Text of this Article]

Root Cause Analysis in Medicine

Author Affiliations: Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (Dr Wu); University of California, San Francisco School of Medicine (Ms Lipshutz); Johns Hopkins School of Medicine, Baltimore, Maryland (Dr Pronovost). Dr Wu is now with the World Alliance for Patient Safety, World Health Organization, Geneva, Switzerland.

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