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Cardiovascular Regeneration and Stem Cell Therapy
Edited by Annarosa Leri, Piero Anversa, and William H. Frishman.
248 pp, $134.95.
Hoboken, NJ, Wiley-Blackwell Publishing, 2007.
ISBN-13 978-1-4051-4842-9.
JAMA. 2008;299(6):700-701.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Stem cell biology and its potential for regenerative medicine is an exciting and fast-moving topic. The cardiovascular community was among the first to translate early experimental results into clinical applications. In fact, large trials are ongoing in which bone marrow cells are used to treat patients after myocardial infarction. However, the efficacy, the potential mechanisms, and the possible risks associated with this treatment are still a matter of controversy. In addition, recent findings suggest that, similar to the central nervous system, endogenous progenitors/stem cells may be present in the adult heart and that these cells could be further exploited for therapeutic purposes. Therefore, Cardiovascular Regeneration and Stem Cell Therapy, edited by Drs Leri, Anversa, and Frishman, is timely and interesting because it summarizes the current data on these topics.
The book covers work ranging from basic stem cell biology to clinical trials using bone marrow cells for cardiac regeneration. . . . [Full Text of this Article]
Bernd K. Fleischmann, MD, Reviewer
Physiologisches Institut
Life & Brain Center
University of Bonn
Bonn, Germany
bernd.fleischmann@uni-bonn.de
Armin Welz, MD, Reviewer
Department of Cardiac Surgery
University of Bonn
armin.welz@ukb.uni-bonn.de
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