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Cardiorespiratory Fitness, Adiposity, and Mortality—Reply
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In Reply: Dr Wei raises a concern about the identical rates of physical inactivity between survivors and decedents. Self-reported physical activity is likely a crude approximation of actual physical activity, and misclassification may be high because activity assessment tends to be incomplete when based on questionnaires such as ours and others.1-2
One of the advantages of the Aerobics Center Longitudinal Study is the objective measure of fitness. It is an open cohort study, and the baseline data were obtained across a broad period of time (eg, 1970-2003) that extends back many years before the emergence of the obesity epidemic. Therefore, the overall prevalence of overweight/obesity aggregated across baseline examination dates should be expected to be lower than observed in later samples, such as the National Health and Nutrition Examination Survey. We agree that adjustment for baseline year may not totally eliminate the possible bias. We therefore adjusted for baseline age . . . [Full Text of this Article]
Xuemei Sui, MD, MPH
msui@gwm.sc.edu
Steven N. Blair, PED
Department of Exercise Science Arnold School of Public Health University of South Carolina Columbia
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