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  Vol. 300 No. 13, October 1, 2008 TABLE OF CONTENTS
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Nonmammographic Screening for Breast Cancer—Reply

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In Reply: Screening for breast cancer is not straightforward. As Hall1 stated, "Screening programs are inherently inefficient because an entire population is subject to the test, but relatively few individuals benefit, and some are actually harmed." The low absolute lifetime risk of death from breast cancer Dr Keen notes may, however, be attributable to earlier diagnosis due to screening. Overdiagnosis is an important concern; however, because breast cancer continues to be one of the most frequent causes of cancer death in women, overdiagnosis may not be the most important issue.2-3 Women witness others experiencing or dying from breast cancer, and this personal exposure is the likely cause of fear of breast cancer many women share. For many women, false-positive diagnoses are considered more tolerable than a late diagnosis of cancer.4

Keen argues that a large number of biopsies are needed to prolong one woman's life. Screening will generally look inefficient . . . [Full Text of this Article]

Christiane K. Kuhl, MD
kuhl@uni-bonn.de
Department of Radiology
University of Bonn
Bonn, Germany



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RELATED ARTICLE

The "Coming of Age" of Nonmammographic Screening for Breast Cancer
Christiane K. Kuhl
JAMA. 2008;299(18):2203-2205.
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RELATED LETTER

Nonmammographic Screening for Breast Cancer
John D. Keen
JAMA. 2008;300(13):1515-1516.
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