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Prenatal Genome Testing Sparks Debate
Bridget M. Kuehn
JAMA. 2008;300(14):1637-1639.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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New technologies that allow scientists to rapidly analyze a person's genome for potentially deleterious variations are now being used by at least 1 company and an academic medical center for prenatal testing, igniting a debate among scientists about the clinical value and ethical implications of the procedure.
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Some scientists say that results of new tests that provide information about a fetus' future genetic risks are often ambiguous and may cause parents unnecessary anxiety.
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As data emerge from early clinical studies that use microarray comparative genomic hybridization for prenatal diagnosis (Sahoo T et al. Genet Med. 2006;8[11]:719-727 and Shaffer LG et al. Prenat Diagn. 2008;28[9]:789-795), proponents of the testing are beginning to offer this expensive service more broadly. But because such tests may provide parents with ambiguous information, some scientists question their clinical value and express concern that the procedure offers false assurances to parents at . . . [Full Text of this Article] COPY NUMBER VARIATIONS
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