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	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In Reply: Dr Balamuthusamy and colleagues question the clinical relevance of asymptomatic thrombotic events. These events did not influence catheter removal in our study because ultrasound evaluations were performed after catheter removal. Review of severe adverse events in the participants identified no case of fatal pulmonary embolism related to the studied catheter. Because critically ill patients included in our study did not undergo systematic pulmonary evaluation or autopsy, I cannot comment further on the risk of pulmonary embolism; however, this topic is discussed in a study by Timsit et al.¹

In response to Dr Eisen, I doubt that the incidence of catheter colonization was heavily overestimated by the landmark technique used for the jugular position because there were consistent results when considering only those in the jugular group with a 100% success rate. The hazard ratio (HR) for colonization between femoral and jugular sites after excluding 131 jugular catheters with . . . [Full Text of this Article]

Jean-Jacques Parienti, MD, DTM&H
parienti-jj@chu-caen.fr
Department of Biostatistics and Clinical Research
Côte de Nacre University Hospital
Caen, France

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