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Sildenafil as Treatment for Antidepressant-Induced Sexual Dysfunction
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To the Editor: Dr Nurnberg and colleagues1 concluded that sildenafil treatment of sexual dysfunction in women using SRIs is associated with a reduction in adverse sexual effects. Regular sexual activity includes masturbation, oral sex, and intercourse. If the sexual activity is with a partner, clinicians need to know the influence of the partner on sexual satisfaction in these women.
The potentially confounding issue of partner characteristics was addressed only in the exclusion criteria: a sexual partner who has or is receiving treatment for sexual dysfunction. However, in analyzing the participants the authors did not consider partner factors, such as the health and relationship activity of the partner or whether the partner is monogamous. It would be valuable to consider the effect on the sexual satisfaction of a woman of a partner who keeps fit by exercising compared with one who is always sedentary.
Another potential confounder is environment. Some women . . . [Full Text of this Article]
Liu Hong, PhD
hongliu180@126.com
Kaichun Wu, PhD;
Daiming Fan, PhD
Institute of Digestive Diseases Fourth Military Medical University Xian, Shaanxi Province, China
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