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  Vol. 300 No. 21, December 3, 2008 TABLE OF CONTENTS
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Framingham Study Insights on the Hazards of Elevated Blood Pressure

Commentary by William B. Kannel, MD, MPH,; Phillip A. Wolf, MD

JAMA. 2008;300(21):2545-2547.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

SUMMARY OF THE ORIGINAL ARTICLE

Epidemiologic Assessment of the Role of Blood Pressure in Stroke: The Framingham Study

William B. Kannel, MD, Philip A. Wolf, MD, Joel Verter, MS, and Patricia M. McNamara

JAMA. 1970;214(2):301-310.

Control of hypertension whether labile or fixed, systolic or diastolic, and at any age or in either sex, appears to be central to the prevention of atherothrombotic brain infarction (ABI). Prospectively, hypertension proved to be the most common and potent precursor of ABIs. Its contribution was direct and could not be attributed to factors related both to stroke and hypertension. Asymptomatic, casual hypertension was associated with a risk of ABI about 4 times that of normotensive individuals. The probability of occurrence of an ABI was predicted no better with both blood pressure measurements or the mean arterial pressure than with systolic alone. Since there . . . [Full Text of this Article]

Author Affiliations: Boston University School of Medicine, Framingham Heart Study, Framingham, Massachusetts.



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