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Bridget M. Kuehn

JAMA. 2008;300(24):2846.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

A combination of medication and behavioral therapy may be the most effective approach for treating children and adolescents with anxiety disorders, according to results from a multicenter clinical trial funded by the National Institute of Mental Health.

The randomized controlled trial involving 488 individuals aged 7 to 17 years with an anxiety disorder compared the effectiveness of 14 sessions of cognitive behavioral therapy, up to 200 mg of sertraline daily, a combination of the two therapies, or a placebo drug for 12 weeks (Walkup JT et al. N Engl J Med. doi: 10.1056 /NEJMoa0804633 [published online ahead of print October 30, 2008]). Of the patients who received the combination therapy, 80.7% were rated as very much or much improved on the Clinician Global Impression-Improvement scale; 59.7% of those receiving cognitive behavioral therapy alone and 54.9% of those taking sertraline alone received the same improvement rating (although . . . [Full Text of this Article]

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