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  Vol. 300 No. 3, July 16, 2008 TABLE OF CONTENTS
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The Estrogen Elixir: A History of Hormone Replacement Therapy in America

By E. S. Watkins
351 pp, $45.50
Baltimore, MD, The Johns Hopkins University Press, 2007
ISBN-13: 978-0-8018-8602-7

JAMA. 2008;300(3):335-336.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

More than 50 million American women,1 both proponents and opponents of menopausal hormone therapy, can quickly appreciate the value of The Estrogen Elixir. This book takes an in-depth, socially analytical look at the evolution of menopausal hormone therapy in the United States, with a focus on estrogen since its discovery. The Estrogen Elixir is divided into 14 chapters spanning 368 pages and enriched by 1102 references and notes. Watkins tells the story accurately and objectively. No accusations and no praise, just the facts.


Figure 80126FA
Molecule data sources: DrugBank Accession No. DB80073, Protein Data Bank ID 1A52.

The first 4 chapters lay the groundwork from historical and public health notions and then link the information to the socially and politically evolving US attitudes concerning menopause. Chapters 5 and 6 unfold the discovery of the link between estrogen and endometrial cancer in the 1970s,2 then take the reader to live, or . . . [Full Text of this Article]

K. Eddie Gabry, MD, MS, Reviewer
Division of Metabolic and Endocrine Products
US Food and Drug Administration Center for Drug Evaluation and Research
Silver Spring, Maryland
gabry@women-health.us



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