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In Reply: We agree with Dr Carney and colleagues that depression is an important condition that is associated with increased risk of morbidity and mortality in patients with heart disease and that warrants effective response by clinicians. The recent AHA science advisory¹ concluded that routine depression screening in heart disease patients would accomplish that, but this recommendation was not based on a careful review of potential benefits and harms that is customary for a statement of this type.² Carney et al do not find fault with the quality or rigor of our systematic review. Yet they support the AHA recommendation even though our review did not find any clinical trial that assessed whether depression screening improves depression or cardiac outcomes in heart disease patients or any other evidence that depression screening would likely benefit patients with cardiovascular disease.

Carney et al question how physicians will identify patients with depression and . . . [Full Text of this Article]

Brett D. Thombs, PhD
brett.thombs@mcgill.ca
Department of Psychiatry
McGill University
Montréal, Québec, Canada

Peter de Jonge, PhD
Interdisciplinary Center for Psychiatric Epidemiology
Department of Psychiatry
University Medical Center Groningen
University of Groningen
Groningen, the Netherlands

Roy C. Ziegelstein, MD
Department of Medicine
Johns Hopkins University School of Medicine
Baltimore, Maryland

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Depression Screening in Patients With Heart Disease
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