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Joan Stephenson, PhD

JAMA. 2009;301(14):1421-1422.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Montreal, Canada—After years of disappointing attempts to develop a vaginal microbicide that helps protect women from HIV infection, researchers announced preliminary findings from the first trial to show promising results.

New findings indicate that an experimental microbicide helps reduce risk of HIV infection. (Photo credit: Microbicide Trials Network/University of Pittsburgh)

In addition to these findings, presented at the 16th Conference on Retroviruses and Opportunistic Infections, other encouraging news on the prevention front came from studies in macaque monkeys that found that antiretroviral drugs, given by mouth or in a vaginal gel, offered some protection to the animals from infection with SHIV, a virus containing components of HIV and a related monkey virus that mimics HIV infection and causes serious illness in macaques.

With no effective HIV vaccine on the horizon, an effective microbicide would be a major component in prevention efforts. Because microbicides can be applied . . . [Full Text of this Article]

MICROBICIDE STUDY



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