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A Perspective for the Early 21st Century

Mary McGrae McDermott, MD; Michael H. Criqui, MD, MPH

JAMA. 2009;301(18):1927-1928.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Lower extremity peripheral artery disease (PAD) is common among older men and women in developed countries and will become increasingly prevalent as populations survive longer with chronic disease. Recent estimates in the United States indicate that 1 in 16 men and women 40 years or older have PAD.¹ In primary care medical practices in the United States, nearly 30% of men and women who are either 70 years or older or aged 50 to 69 years with a history of diabetes or smoking have an ankle-brachial index (ABI) of less than 0.90, consistent with PAD.²

Multiple epidemiological studies completed during the past 20 years consistently demonstrate increased rates of cardiovascular morbidity and mortality among men and women with PAD compared with those without PAD even after adjusting for cardiovascular disease risk factors and history of cardiovascular events.^3-4 Therefore, preventing cardiovascular events . . . [Full Text of this Article]

Author Affiliations: Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois (Dr McDermott); and Department of Family and Preventive Medicine, and Department of Medicine, University of California, San Diego School of Medicine, San Diego (Dr Criqui). Dr McDermott is a Contributing Editor, JAMA.

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