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Alan H. Friedman, MD

JAMA. 2009;301(19):2044-2045.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The intraoperative floppy iris syndrome (IFIS) was first described by Chang and Campbell in 2005.¹ These authors¹ and others² observed that there was a tendency for poor pupillary dilation and the intraoperative triad of the billowing of a flaccid iris, the propensity for iris prolapse, and progressive intraoperative pupillary constriction. In the current technique ophthalmologists perform cataract surgery through a 2.5-mm incision. A widely dilated pupil is essential for complication-free surgery. Billowing of the iris into the surgical field and poor pupillary constriction are potentially catastrophic barriers to successful surgery. Intraoperative floppy iris syndrome is encountered mainly in cataract surgery and in prospective studies has been found to occur in 2% to 3% of all cataract operations and to a lesser extent in glaucoma surgery.³

The strong association of IFIS with systemic (oral) administration of the _1a- selective adrenergic antagonist tamsulosin, the commonly prescribed medication for . . . [Full Text of this Article]

Author Affiliations: Departments of Ophthalmology and Pathology, The Mount Sinai School of Medicine, New York, New York.

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